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A Newsletter Exploring
Biomedical Research Issues For Middle & High School Educators
Vol. 1, Issue 6, Fall 2003
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Focus
NOTEWORTHY PATHOLOGISTS
Peter C. Doherty Shared the 1996 Nobel Prize for his work on the
cellular immune response to viral infections. The knowledge provides a
better platform for the construction of new vaccines. Dr. Doherty is an
Australian veterinarian who currently does his research at St. Jude's
Children's Hospital in Memphis, Tennessee. His autobiography is on the
Nobel website and is a very good read.
Tracey McNamara Dr. McNamara is head pathologist at the Bronx Zoo in New York and
was the first to recognize West Nile virus.
Read her story.
SOCIETY OF TOXICOLOGY
The society has a very informative website
offering excellent materials and public
outreach programs, including "Paracelsus
Goes to School", workshops for K-12
teachers.
Spotlight on Michigan Pathologist
Dr. Crissman, who contributed the article on the front page, works as a
toxicologic veterinary pathologist for Dow Corning. He attended
undergraduate and veterinary school at Michigan State, and, after a
manure-covered year in a dairy cow practice in Ohio, did his pathology
residency and graduate training at Cornell University in Ithaca, NY. He
has published more than twenty scientific journal articles as well as a
small book of poems titled Jailbait in Holy Water. He grew up as one of
eight kids on a farm near Caledonia, Michigan, where he was active in
4-H and showed beef cattle and sheep. Jim is an avid bicyclist, both
road and mountain bikes, and is largely responsible for the mountain
bike singletrack in the Midland City Forest. He also loves crosscountry
and downhill skiing, fly fishing, bow hunting, and writing. Jim and his
wife, Dr. Jill Haver-Crissman, also a veterinarian, have three children
and live on a small farm near Midland with assorted horses, dogs, cats,
and the odd amphibian held captive by their youngest.
A Few Pathology & Toxicology Terms
By James W. Crissman, D.V.M., Ph.D.
Pathology: The study of the structural or functional changes in
the body that cause or are caused by disease.
Lesion: Any pathological change in the structure or function of a
body part.
Biopsy: The removal and examination of tissue (usually
microscopic) to establish a diagnosis.
Cancer: An abnormal proliferation of cells, which may originate
in any tissue, and which in its natural unchecked course, will kill the
host. Many cancers can now be treated effectively, especially if
discovered early.
Malignant & Benign: These words are used to describe many
pathologic processes, but especially tumors. Benign tumors grow slowly
in place and often may be easily removed or even sometimes ignored.
Malignant tumors are cancerous; they spread by local invasion or
metastasis to other parts of the body. The line between benign and
malignant is not always clear, and some benign tumors can become
malignant.
Autopsy/Necropsy: The post mortem (after death) examination of a
body to characterize disease processes or traumatic injuries, especially
to determine the cause of death. The term autopsy is used for humans
(auto = self); necropsy is used for animals.
Toxicology: The scientific study of the toxic properties of
natural and synthetic chemicals. This includes learning what happens in
the body at high dose levels and what dose is harmless.
Paracelsus: (1493—1541) Swiss physician and alchemist, and
perhaps the father of modern toxicology. He is most remembered for this
fundamental principle: "What is it that is not poison? All things are
poison and nothing is without poison. It is only the dose that makes a
thing not a poison." Or, as your mother might say: "All things in
moderation, dear."
BioFocus
Biofocus is published by the Michigan Society for Medical Research. Please send your questions, comments, and suggestions to:
MISMR
P.O. Box 3237
Ann Arbor, MI 48106-3237
Voice: (734) 763-8029
Fax: (734) 930-1568
Email: MISMR@umich.edu
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